PATENTED INVENTIONS

The specialists of BIOTEHNOS are authors of over 50 patents and patent applications under examination at the State Offices for Inventions and Trademarks from Romania and in other countries.The products making the subject matter of the patents cover various areas, such as: technological process units, biopharmaceuticals and biocosmetics.
The first invention, structured waters, is also an absolute world-wide finding, leading to a lot of scientific, technological and industrial applications in many and various fields such as: medicine, biology, electrochemistry, bioenergetics, pharmaceutical and cosmetic industry, agriculture a.s.o.
The patents granted in the USA and European Union has opened the doors to the world competition in the top field of biotechnology, aiming to finding a valuable place on the international market.

PATENTED INVENTIONS IN ROMANIA

     1) Methods and technological plants for water structuring: RO 107628, RO 107629, RO 108233, RO 108335, RO 108724, RO 109835, RO 109836, RO 106376, RO 96192, RO 88053, RO 88054, RO 117503, RO118096

     2) Pharmaceutical products and technologies:

  • for treatment of wounds and burns: RO 107087, RO 115698, RO 118631, RO 121675
  • antirheumatics: RO 110124, RO 115696, RO 118630, RO 120948, RO 120608 
  • for treatment of breathing system: RO 109274, RO 115778, RO 116767, RO 118632, RO 118629
  • vascular trophic gel: RO 112409

    3) New raw materials, biotechnological semi-products for drug and cosmetic industries: RO 109504, RO 110202, RO 108356, RO 112473, RO 115699, RO 116869, RO 116870, RO 116871, RO 116872, RO 116867, RO 118557

     4) Cosmetic products and technologies:

  • cosmetic creams: RO 107544, RO 107545, RO 107546, RO 109997, RO 116865, RO 117295; applications: RO 01-01280, 01-01281

     5) Other methods and plants:

  • colorimetric methods: RO 110566, RO 110565 and RO 109787
  • depolluting method: RO 107922
  • automated device for non-destructive refreshing of culture medium: RO 111112
  • growth stimulating methods for cultures of:
    • biologically active substances - producing actinomycetes: RO 88056
    • antibiotics - producing fungi: RO 88057
    • biologically active substances - producing bacteria: RO 88058
  • method for diminishing the resistance of pathogenic germs to antibiotics: RO 88059
  • method for stimulating fermentative processes to produce biosynthesis proteins: RO 88055

 PATENTED INVENTIONS ABROAD


  • "Plant and Process for Archieving Structured Waters of the "I" type Inhibitively Activated and "S" type Stimulatively Activated"
    USA - US Patent no. 5846397/8.12.1998;
    European Patent (CH, DE,  GB, IT, NL, SE) - EP no. 0777631/3.11.1999;
    Mexican Patent no. 209091/22.07.2002;
    China Patent no.: ZL 95194722.2/28.02.2003

  • "Planta y Processo Para Lograr Aguas Estructuradas del Tipo "I" Activadas Inhibitivamente y Tipo "S" Activadas Estimulativamente"

     Republica de Colombia Patente de Invencion - Certificado No. 26346/29.02.2000

  • "Bioactive Concentrate, its Producing Method and Certain Drug Compositions Containing also Chondroitin Sulphate"

    USA - US Patent no. 5965151/12.10.1999;
    European Patent (CH, DE, GB, IT, BE, FR) no. EP 0820293/12.09.2002;
    Ukrainean Patent no. UA 46764/17.06.2002;
    China - Patent no. ZL 96193190.6/25.04.2003

  • "Concentrato Bioactivo, Procedimiento Para Obtenerlo y Composiciones Medicamentosas"

     Columbia Patent no. 26809/30.11.2001

    INVENTIONS HAVING REGISTERED APPLICATIONS FOR PATENTING ABROAD

    • "Planta y Processo Para Lograr Aguas Estructuradas del Tipo "I" Actavadas Inhibitivamente y Tipo "S" Activadas Estimulativamente"

    Inscripcion No.: 1471/95/22.08.1995 (Venezuela) - the patent granting decision was issued 

    • "Concentrato Bioactivo, Procedimiento Para Obtenerlo y Composiciones Medicamentosas"

    Inscripcion no.: 0593/96/10.04.1996 (Venezuela)

    AWARDED PATENTS

    International Invention Fair London - 2000
    • Plant and Process for Achieving Structured Waters of "I"-Inhibitively and "S" - Stimulatively Activated Types
      Authors: Manzatu I; Ionita-Manzatu V.
      Patents no.: RO 109835; US 584639/1998; EP 0777631/1999
      PCT Application no.: RO 95/00010;
      Venezuela Application no.: 1471/95
      Colombia Application no.: 95-62408
      GOLD MEDAL
    • Bioactive Concentrate, its Producing Method and Drug Compositions - ALFLUTOP
      Authors: Manzatu I.; Arizan D.; Ionita-Manzatu V.; Carasava M.; Panait M.; Scarlat I.
      Patent no.: RO 110124
      Patent USA no.: US 5965151/1999
      MENTION

    Second Inventions Olympiad GENIUS 2000

    International Fair of Inventions Budapest

    The JEROME CUP for multiple inventions of high quality for Prof. Ioan Manzatu

    • Method and Installation for Recording and Analysis of Electroluminiscent Emissions

      Authors: Manzatu I; Mamulas I. Caracaleanu D..
      Patent Application no.: RO 2000-00310;
      GENIUS MEDAL

    • Process for Separation and Obtention of Some Groups of Bioctive Components from Hyppophae Rhamnoides and the Product Based on Them

      Authors: Manzatu I.; Tamas V.; Rosca I.
      Patent Application no.: RO 2000-00309
      BRONZE MEDAL

    International Exhibition of Inventions Geneve - 2000

    • Process and Plant for Obtaining "Memory Aqueous Solutions"

    Authors: Manzatu I.; Caracaleanu D.
    Patent no.: RO 108233
    SILVER MEDAL

    •  Biounda Line - Cosmetic Active Base, Cosmetic Formulas and Preparing Process

    Authors: Manzatu I., Speteanu R., Manzatu L., Motoaga V.
    Patent Application no.: RO 099-282
    SILVER MEDAL 

    • Method and Installation for Recording and Analysis of Electroluminiscent Emissions

    Authors: Manzatu I., Mamulas T., Caracaleanu D.
    Patent Application no.: RO 2000-0031
    BRONZE MEDAL

    • Process for Separation and Obtention of Some Groups of Bioactive Components from Hyppophae Rhamnoides and the Product Based on Them

    Authors: Manzatu I., Tamas V., Rosca I.
    Patent Application no.: RO 2000-00309
    BRONZE MEDAL

    EUREKA'99

    International Exhibition of Inventions - Bruxelles

    • Plant and Process for Achieving Structured Waters of "I"- inhibitively and "S" - stimulatively Activated Types

    Authors: Manzatu I., Tamas V., Rosca I.
    Patents no.: RO 109835, US 584639/1998, EP 0777631/1999
    Patent Applications no.: PCT/RO 95/00010
    Venezuela no.: 1471/95
    Columbia no.: 95-62408
    GOLD MEDAL WITH MENTION OF THE JURY

    • Process and Plant for Obtaining "Memory" Aqueous Solutions

    Authors: Manzatu I., Caracaleanu D.
    Patent no.: RO 108233
    GOLD MEDAL WITH MENTION OF THE JURY

    • A Natural Product from Certain Fir and Pine Spruce Resin and its Preparing Method - BIOCON

    Authors: Manzatu I., Tamas V., Peia M.
    Patent Application no.: RO 109504
    GOLD MEDAL

    • Process for Obtaining some Bioactive Intermediates from Plants

    Authors: Manzatu I., Popescu M., Zglimbea L.
    Patent Application no.: RO 98-00385
    GOLD MEDAL

    • Process for Obtaining Lyophilized Bioactive Extracts of Plants

    Authors: Manzatu I., Popescu M.; Zglimbea L.
    Patent Application no.: RO 98-00386
    SILVER MEDAL

    • Process for Obtaining Lyophilized Bioactive Extracts of Plants Utilizable in Cosmetics

    Authors: Manzatu I., Popescu M., Zglimbea L.
    Patent Application no.: RO 98-00387
    BRONZE MEDAL

    International Exhibition of Inventions Geneve - 1999

    • A Natural Product from Fir and Pine Spruce Resin and its Preparing Method-BIOCON

    Authors: Manzatu I., Tamas V., Peia M.
    Patent Application no.: RO 109504
    GOLD MEDAL

    • Process for Changing Bioenergetic Properties of Microorganisms

    Authors: Manzatu I., Caracaleanu D.
    Patent Application no.: RO 108335
    GOLD MEDAL

    • Method and Plant for Determining the Energetic Changes in Structured Aqueous Solutions

    Authors: Manzatu I., Caracaleanu D.
    Patent Application no.: RO 108335
    GOLD MEDAL

    • Bioactive Concentrate, its Producing Method and Drug Compositions - ALFLUTOP®

    Authors: Manzatu I., Arizan D., Ionita-Manzatu V., Carasava M., Panait M., Scarlat I.
    Patent no.: RO 110124, Patent USA no.: US 5965151-1999
    SILVER MEDAL

    • Chrysalis Oil and its Producing Method

    Authors: Manzatu I., Tamas V., Brasla A., Constantinescu M., Barcutan C.
    Patent no.: RO 110202
    SILVER MEDAL

    • Topical Products and their Pharmaceutical Formulations for Human and/or Veterinary Use and their Process: ARMON®, OFTALMOSALVA®, VARISALVA®, ESCASALVA®, CERVISALVA®, ARMIGEL®, SALVADERM®, SALVAPODERM®

    Authors: Manzatu I., Ionita-Manzatu I., Carasava M.
    Patent no.: RO 107087
    Patent Application no.: RO 97-00866
    SILVER MEDAL

    • Vascular Trophic Gel and Producing Method - TROFIGEL®

    Authors: Manzatu I., Tamas V., Ghica M.
    Patent no.: RO 112409
    BRONZE MEDAL

    • Natural Medicinal Drugs for Otorhinolaryngologic and Stomatologic Use and their Producing Methods - GELISEPT®, RHINOGEL®,PAROGEL®

    Authors: Manzatu I., Tamas V., Dobos R., Arizan D, Peia M., Rizopol V., Ciocarlan M., Cioban E.
    Patent no.: RO 109274
    Patent Application no.: RO 97-00931; 97-01580; 95-00755
    BRONZE MEDAL

    International Exhibition of Inventions Geneve - 1996

    • Process and Plant for Liquid Solutions Activating and Structuring in Co-operative Fields

    Authors: Manzatu I., Caracaleanu D.
    Patents no.: RO 107628 B1, RO 107629 B1, RO 108233 B1, RO 108355 B1, RO 108742 B1
    GOLD MEDAL

    • Plant and Process for Achieving Structured Waters of "I"-inhibitively and "S"-stimulatively Activated Types

    Authors: Manzatu I., Ionita-Manzatu V.
    Patents no.: RO 109835; US 5846397, EP 0777631/19991
    PCT Application no.: RO 95/00010
    Venezuela Application no.: 1471/95
    Columbia Application no.: 95-62408
    GOLD MEDAL

    • Biounda Line-Cosmetic Creams

    Authors: Manzatu I., Juravle Gh., Dobrescu D., Juravle V., Carasava M.
    Patents no.: RO 107544, RO 107545, RO 107546
    GOLD MEDAL

    • Magnetic Field Treatment Device for Water and Aqueous Solutions

    Authors: Ionita-Manzatu M., Ionita-Manzatu V., Manzatu I., Domsa F.
    Patent no.: RO 109836
    GOLDEN SILVER MEDAL

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